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In animal models finerenone reduced the expression of genes encoding monocyte chemoattractant protein-1, matrix metalloproteinase-2 and plasminogen activator inhibitor-1 (related to tissue remodelling and fibrosis) in the kidney, and additionally demonstrated beneficial immunomodulatory effects [73]

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The Mayo Clinic Diet: Behind the Trademark Plan The Mayo Clinic diet, created by the organization, stresses the importance of cutting calories, while including more whole grains, fruits and vegetables for weight loss

and micronutrient or protein supplementation as needed